Tilmicosin Phosphate

* 20-deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin phosphate;

* TILMICOSIN PHOSPHATE;

* tilmicosina fosfato;

* TilMicosin Base( Phosphate);

* 20-Deoxy-20-(3,5-diMethylpiperidin-1-yl)-desMycosin phosphate;

* tilmicosin phosphate(animal use);

* Phosphate Tilmicosin

Appearance: White to off-white powder

Assay (HPLC): ≥ 98% Identification: IR/UV spectrum complies

Loss on Drying: ≤ 1.0%

Residual Solvents: Within ICH limits

Heavy Metals: ≤ 10 ppm

Mode of Action: Binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis. Acts as a bacteriostatic macrolide but can be bactericidal at high concentrations.  

Spectrum: Strong activity against Gram-positive bacteria and some Gram-negative bacteria. Particularly effective against respiratory pathogens: Pasteurella multocida, Mannheimia haemolytica, Actinobacillus pleuropneumoniae, Mycoplasma spp. Limited effect on Enterobacteriaceae.  

Additional Effects: High affinity for lung tissue, ensuring strong efficacy in respiratory infections. Long half-life, allowing sustained activity. Key Features: Veterinary macrolide antibiotic. Widely used for prevention and treatment of bovine respiratory disease (BRD), ovine respiratory disease, and swine respiratory disease. Administered via feed, water, or injection (caution: cardiotoxic if administered intravenously in animals).  

In short: Tilmicosin phosphate is a macrolide antibiotic with excellent lung distribution, widely used in veterinary medicine to control respiratory infections in cattle, sheep, and swine.