Fenbendazole

* Fenbendazolum [INN-Latin],
* 2-(Methoxycarbonylamino)-5-(phenylthio)benzimidazole,
* Methyl (5-(phenylthio)-1H-benzimidazol-2-yl)carbamate,
* [5-(Phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester,
* 2-Benzimidazolecarbamic acid, 5-(phenylthio)- methyl ester,
* AIDS-007898,

* AIDS007898,
* Carbamic acid, (5-(phenylthio)-1H-benzimidazol-2-yl)-, methyl ester,
* Carbamic acid, [5-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester,
* CCRIS 7309,

* CHEMBANK903,

* EINECS 256-145-7,

* F5396,
* Fenbendazol [INN-Spanish],

*fenbendazole,

*Fenbendazole [USAN:BAN:INN],
*HOE 881,

*Hoe 881v,

*HOE-881v,
*Methyl 5-(phenylsulfanyl)-1H-benzimidazol-2-ylcarbamate,
*Methyl 5-(phenylthio)-2-benzimidazolecarbamate,

*ZINC00121553,
*MLS000069723,

*Panacur,

*Phenbendasol,

*Safe-gard,

*SMR000058217,

Appearance: White to off-white crystalline powder

Assay: ≥ 98% (API standard)

Solubility: Practically insoluble in water; soluble in some organic solvents

Common dosage forms: Oral suspension, tablet, paste, premix, bolus (for veterinary and human use)

Mode of Action: Benzimidazole anthelmintic; binds to β-tubulin in parasites, inhibiting microtubule formation → blocks glucose uptake → energy depletion → parasite death.  

Spectrum: Broad-spectrum; effective against gastrointestinal nematodes, lungworms, and many cestodes (tapeworms). Also has ovicidal activity (acts on parasite eggs).  

Key Features: Effective against both adult and immature stages of many parasites Widely used in veterinary medicine (ruminants, horses, swine, pets) and sometimes in humans Low water solubility; formulations improve bioavailability Generally well tolerated with a good safety margin  

In short:  Fenbendazole is a broad-spectrum benzimidazole anthelmintic that kills parasites by blocking microtubules and starving them of energy, effective against nematodes, some cestodes, and lungworms.