Triclabendazole is a benzimidazole anthelmintic uniquely effective against liver flukes at all stages, making it the treatment of choice for fascioliasis.
Product Description
| Synonyms |
* Triclabendazolum [INN-Latin], * Triclabendazol [INN-Spanish], |
| Chemical Name | 6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzoimidazole |
| Molecular formula | C14H9Cl3N2OS |
| Molecular weight | 359.658 |
| CAS No. | 68786-66-3 |
| Structural formula |  |
| Specification |
Appearance: White to off-white crystalline powder Assay (HPLC): ≥ 98% Identification: IR/UV spectrum complies Melting Point: 175–180 °C Loss on Drying: ≤ 0.5% Residual Solvents: Within ICH limits Heavy Metals: ≤ 10 ppm |
| Pharmacodynamic Properties |
Mode of Action: Binds to β-tubulin in the parasite, inhibiting microtubule formation and glucose uptake, leading to energy depletion and death. Spectrum: Highly specific activity against liver flukes (Fasciola hepatica and Fasciola gigantica). Effective against both immature and adult stages. Limited or no efficacy against nematodes, cestodes, or other trematodes. Additional Effects: Provides complete flukicidal activity with a single dose. Retains effectiveness even against immature liver flukes, unlike most other benzimidazoles. Key Features: Benzimidazole derivative with unique spectrum. Drug of choice for fascioliasis in both human and veterinary medicine. High efficacy, low toxicity, and well tolerated. In short: Triclabendazole is a benzimidazole anthelmintic uniquely effective against liver flukes at all stages, making it the treatment of choice for fascioliasis. |
| Storage | Store in a tightly sealed container. Keep in a cool, dry place (15–25 °C). Protect from light and moisture. |
| MSDS | Provide as per request after the order or contract is signed. |
● Packaging method: 1kg aluminum foil bag, 25kg cardboard or fiber drum, 25kg aluminum tin
● Transportation methods: sea freight, air freight, land freight, international express (DHL, FEDEX, UPS, etc.) are all available
