Niclosamide is a well-established anthelmintic drug used primarily for intestinal tapeworm infections, working by disrupting parasite energy metabolism in the gut.
Product Description
| Synonyms | * 2', 5-Dichlor-4'-nitro-salizylsaeureanilid, * 2', 5-Dichloro-4'-nitrosalicylanilide, * 2',5-Dichlor-4'-nitro-salizylsaeureanilid,* 2',5-Dichlor-4'-nitro-salizylsaeureanilid [German], * 2',5-Dichloro-4'-nitrosalicyanilide, * 2-Chloro-4-nitrophenylamide-6-chlorosalicylic acid, * 2-Hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide, * 5-Chloro-2'-chloro-4'-nitrosalicylanilide, * 5-Chloro-N-(2'-chloro-4'-nitrophenyl)salicylamide, * 5-Chloro-N-(2-chloro-4-nitro-phenyl)-2-hydroxy-benzamide, * 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide, * 5-Chlorosalicyloyl-(o-chloro-p-nitranilide), * AI3-25823, * AIDS-092503, * AIDS092503, * Atenase, * BAY 2353, * Bayer 2353, * Bayer 73, * Bayluscid, * Benzamide, 5-chloro-N- (2-chloro-4-nitrophenyl)-2-hydroxy-, * Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-, * BRN 2820605, * C07265, * CCRIS 3437, * Cestocid, * Cestocide, * Chemagro 2353, * CHEMBANK1313, * CHEMBANK4413, * Clonitralid, * Devermin, * Devermine, * Dichlosale, * EINECS 200-056-8, * ENT 25823, * Fedal-Telmin, * Fenasal, * Helmiantin, * HL 2447, * HSDB 1572, * Iomesan, * Iomezan, * Lintex, * Mansonil, * Mato, * N-(2'-Chlor-4'-nitrophenyl)-5-chlorsalicylamid, * N-(2'-Chlor-4'-nitrophenyl)-5-chlorsalicylamid [German], * N-(2'-Chloro-4'-nitrophenyl)-5-chlorosalicylamide, * N-(2-Chloro-4-nitrophenyl)-5-chlorosalicylamide, * N3510, * Nasemo, * Niclocide, * Niclocide (TN), * Niclosamida [INN-Spanish], * Niclosamide, * Niclosamide [BSI:ISO], * Niclosamide [USAN:BAN:INN], * Niclosamidum [INN-Latin], * nicolsamide, * Nitrophenyl chlorsalicylamide, * Sagimid, * NSC 178296, * NSC178296, * Phenasal, * Radeverm, * Ruby, * Salicylanilide, 2',5-dichloro-4'-nitro-, * SR 73, * Sulqui, * Telidal, * Tredemine, * Vermitid, * Vermitin, * WR 46234, * Yomensan, * Yomesan, * Zestocarp |
| Chemical Name | 2',5-dichloro-4'-nitrosalicylanilide |
| Molecular formula | C13H8Cl2N2O44 |
| Molecular weight | 327.119 |
| CAS No. | 50-65-7 |
| Structural formula |  |
| Specification |
Appearance: Yellowish to light brown crystalline powder Assay (HPLC): ≥ 98% Identification: IR/UV spectrum complies Melting Point: 225–230 °C Loss on Drying: ≤ 0.5% Residual Solvents: Within ICH limits Heavy Metals: ≤ 10 ppm |
| Pharmacodynamic Properties |
Mode of Action: Uncouples oxidative phosphorylation in parasite mitochondria, preventing energy production. This leads to rapid depletion of ATP and parasite death. Spectrum: Highly effective against cestodes (tapeworms) such as Taenia saginata, Taenia solium, Diphyllobothrium latum, and Hymenolepis nana. Limited or no efficacy against nematodes or trematodes. Additional Effects: Used as a veterinary and human anthelmintic. Has been investigated for anticancer, antiviral, and antifungal potential in research. Key Features: Poor systemic absorption → acts primarily within the intestinal lumen. Considered safe due to minimal systemic exposure. Often given as chewable tablets for ease of administration. In short: Niclosamide is a well-established anthelmintic drug used primarily for intestinal tapeworm infections, working by disrupting parasite energy metabolism in the gut. |
| Storage | Store in a tightly sealed container. Keep in a cool, dry place (15–25 °C). Protect from light and moisture. |
| MSDS | Provide as per request after the order or contract is signed. |
● Packaging method: 1kg aluminum foil bag, 25kg cardboard or fiber drum, 25kg aluminum tin
● Transportation methods: sea freight, air freight, land freight, international express (DHL, FEDEX, UPS, etc.) are all available
